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Literature summary for 2.7.11.4 extracted from

  • Krishnan, B.; Massilamany, C.; Basavalingappa, R.H.; Gangaplara, A.; Kang, G.; Li, Q.; Uzal, F.A.; Strande, J.L.; Delhon, G.A.; Riethoven, J.J.; Steffen, D.; Reddy, J.
    Branched chain alpha-ketoacid dehydrogenase kinase 111-130, a T cell epitope that induces both autoimmune myocarditis and hepatitis in A/J mice (2017), Immun. Inflamm. Dis., 5, 421-434 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.4

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Mus musculus 5739
-

Organism

Organism UniProt Comment Textmining
Mus musculus O55028
-
-

Synonyms

Synonyms Comment Organism
BCKDK
-
 Mus musculus
branched chain alpha-ketoacid dehydrogenase kinase
-
 Mus musculus

General Information

General Information Comment Organism
physiological function BCKDk contains multiple epitopes that can induce myocarditis. The BCKDk 111-130 is the primary epitope that induces both autoimmune myocarditis and hepatitis in A/J mice. The disease induced by BCKDk peptides can serve as a useful model to study the autoimmune events of inflammatory heart and liver diseases Mus musculus