Literature summary for 2.7.11.4 extracted from

Zigler, J.S.; Hodgkinson, C.A.; Wright, M.; Klise, A.; Sundin, O.; Broman, K.W.; Hejtmancik, F.; Huang, H.; Patek, B.; Sergeev, Y.; Hose, S.; Brayton, C.; Xaiodong, J.; Vasquez, D.; Maragakis, N.; Mori, S.; Goldman, D.; Hoke, A.; Sinha, D.
A spontaneous missense mutation in branched chain keto acid dehydrogenase kinase in the rat affects both the central and peripheral nervous systems (2016), PLoS ONE, 11, e0160447.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Rattus norvegicus	5739	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + [branched-chain keto-acid dehydrogenase (acetyl-transferring)]	Rattus norvegicus	the enzyme phosphorylates Ser293 of the E1alpha subunit of branched-chain keto-acid dehydrogenase	ADP + [branched-chain keto-acid dehydrogenase (acetyl-transferring)] phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	Q00972	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + [branched-chain keto-acid dehydrogenase (acetyl-transferring)]	the enzyme phosphorylates Ser293 of the E1alpha subunit of branched-chain keto-acid dehydrogenase	Rattus norvegicus	ADP + [branched-chain keto-acid dehydrogenase (acetyl-transferring)] phosphate	-	?

Synonyms

Synonyms	Comment	Organism
BCKDK	-	Rattus norvegicus
branched chain keto acid dehydrogenase kinase	-	Rattus norvegicus
branched-chain alpha-keto dehydrogenase kinase	-	Rattus norvegicus

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Release 2023.1 (January 2023)