Activating Compound | Comment | Organism | Structure |
---|---|---|---|
AMP | - |
Rattus norvegicus |
Cloned (Comment) | Organism |
---|---|
expression of short hairpin RNA for GFP-tagged AMPHalpha subunit in rat ventromedial hypothalamus via injection of the adeno-associated viral vector | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | downregulation of AMPK by microinjection of AMPK-RNAi in ventromedial hypothalamus results in suppressed glucagon and reduction of AMPKalpha-2 isozyme, but not of AMPKalpha-1 isozyme | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Sprague-Dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
hypothalamus | ventromedial hypothalamus | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AMP-activated protein kinase | - |
Rattus norvegicus |
AMPK | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus |