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Literature summary for 2.7.11.26 extracted from

  • Takahashi, M.; Tomizawa, K.; Ishiguro, K.; Takamatsu, M.; Fujita, S.C.; Imahori, K.
    Involvement of tau protein kinase I in paired helical filament-like phosphorylation of the juvenile tau in rat brain (1995), J. Neurochem., 64, 1759-1768.
    View publication on PubMed

Application

Application Comment Organism
medicine brain pathology in investigation of Alzheimers's disease, human tau phosphorylated by the kinase carries an epitope of the paired helical filaments that accumulate in the brain Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + protein tau Rattus norvegicus
-
ADP + protein tau phosphate
-
?
ATP + protein tau Rattus norvegicus Wistar
-
ADP + protein tau phosphate
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
Wistar
-
Rattus norvegicus Wistar
-
Wistar
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-
embryo
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + protein tau
-
Rattus norvegicus ADP + protein tau phosphate
-
?
ATP + protein tau
-
Rattus norvegicus Wistar ADP + protein tau phosphate
-
?

Synonyms

Synonyms Comment Organism
TPKI
-
Rattus norvegicus