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Literature summary for 2.7.11.24 extracted from

  • Hsu, C.Y.; Bristow, R.; Cha, M.S.; Wang, B.G.; Ho, C.L.; Kurman, R.J.; Wang, T.L.; Shih Ie, M.
    Characterization of active mitogen-activated protein kinase in ovarian serous carcinomas (2004), Clin. Cancer Res., 10, 6432-6436.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information MAPKs are up-regulated by upstream kinases such as BRAF and KRAS Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens MAPKs play a pivotal role in signal transduction ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
ovarian serous carcinoma cell 207 different sources, MAPK expression and immunohistochemical analysis, mutational analysis of up-regulating kinases BRAF and KRAS Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information MAPKs play a pivotal role in signal transduction Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
MAPK
-
Homo sapiens