Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | inhibition of the phosphatidylserine-receptor activates ERK and TGF-beta production in vivo | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
U0126 | specific inhibitor of ERK | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | ERK, but not p38 and JNK, is involved in TGF-beta production in macrophages, the phosphatidylserine-receptor is involved in the ERK signaling pathway, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
male C3H/HeN mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
macrophage | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | ERK, but not p38 and JNK, is involved in TGF-beta production in macrophages, the phosphatidylserine-receptor is involved in the ERK signaling pathway, overview | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ERK | - |
Mus musculus |
MAP kinase | - |
Mus musculus |