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Literature summary for 2.7.11.24 extracted from

  • Wang, X.S.; Diener, K.; Manthey, C.L.; Wang, S.; Rosenzweig, B.; Bray, J.; Delaney, J.; Cole, C.N.; Chan-Hui, P.Y.; Mantlo, N.; Lichenstein, H.S.; Zukowski, M.; Yao, Z.
    Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase (1997), J. Biol. Chem., 272, 23668-23674.
    View publication on PubMed
Search for more literature for 2.7.11.24

Activating Compound

Activating Compound Comment Organism Structure
MKK3 strongly activates Homo sapiens
MKK6 strongly activates Homo sapiens
additional information activated by cellular stress and proinflammatory cytokines Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information p38alpha kinase inhibitor AMG 2372 minimally inhibits the kinase activity of p38delta Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme is activated by cellular stresses and plays an important role in regulating gene expression ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens O15264
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland highly expressed in Homo sapiens
-
salivary gland highly expressed in Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no phosphorylation of MAPK-activated protein kinase-2 and -3 Homo sapiens ?
-
 ?
additional information enzyme is activated by cellular stresses and plays an important role in regulating gene expression Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
mitogen-activated protein kinase 13
-
 Homo sapiens