Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(hydroxy-2-naphthalenylmethyl)phosphonic acid | inhibits the insulin receptor tyrosine kinase, IC50 is 0.01 mM | eukaryota | |
additional information | synthesis of peptides behaving as pseudosubstrates, determination of inhibitory potential | eukaryota |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
eukaryota |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | eukaryota | - |
ADP + a phosphoprotein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
eukaryota | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | autophosphorylation near the pseudosubstrate site | eukaryota |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | - |
eukaryota | ADP + a phosphoprotein | - |
? | |
additional information | substrate specificity | eukaryota | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
receptor-linked ribosomal protein S6 | - |
eukaryota |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
eukaryota |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Ki values of the pseudosubstrates in nano- to micromolar range | eukaryota |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.01 | - |
inhibits the insulin receptor tyrosine kinase, IC50 is 0.01 mM | eukaryota | (hydroxy-2-naphthalenylmethyl)phosphonic acid |