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Literature summary for 2.7.11.22 extracted from

  • Kim, H.S.; Lee, W.J.; Lee, S.W.; Chae, H.W.; Kim, D.H.; Oh, Y.
    Insulin-like growth factor binding protein-3 induces G1 cell cycle arrest with inhibition of cyclin-dependent kinase 2 and 4 in MCF-7 human breast cancer C´cells (2009), Horm. Metab. Res., 42, 165-172.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
insulin-like growth factor binding protein-3 decreases the phosphorylation activity of CDK2 and CDK4 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MCF-7 cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
CDK2
-
 Homo sapiens
CDK4
-
 Homo sapiens
cyclin-dependent kinase 2
-
 Homo sapiens
cyclin-dependent kinase 4
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens
cyclin
-
 Homo sapiens