Activating Compound | Comment | Organism | Structure |
---|---|---|---|
p35 | - |
Danio rerio | |
p39 | - |
Danio rerio |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | - |
Danio rerio | - |
Synonyms | Comment | Organism |
---|---|---|
Cdk5 | - |
Danio rerio |
cyclin-dependent kinase 5 | - |
Danio rerio |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Danio rerio | |
cyclin | - |
Danio rerio |
General Information | Comment | Organism |
---|---|---|
malfunction | cdk5 knockdown results in supernumerary spinal and cranial motor neurons. While a dominant negative, kinase-dead cdk5 promotes the generation of supernumerary motor neurons, over-expression of cdk5 suppresses motor neuron development | Danio rerio |
physiological function | cdk5 plays a critical role in spinal and cranial motor neuron development | Danio rerio |