Activating Compound | Comment | Organism | Structure |
---|---|---|---|
p35 | activation of Cdk5 requires association with two noncyclin neural-specific activators p35 and p39 | Mus musculus | |
p39 | activation of Cdk5 requires association with two noncyclin neural-specific activators p35 and p39 | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neuron | - |
Mus musculus | - |
retina | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + B-cell lymphoma protein 2 | B-cell lymphoma protein 2 is phosphorylated at Ser70, Cdk5-mediated B-cell lymphoma protein 2 phosphorylation is pivotal for the antiapoptotic effect of Bcl-2 and contributes to the maintenance of neuronal survival by Cdk5 | Mus musculus | ADP + phosphorylated B-cell lymphoma protein 2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cdk5 | - |
Mus musculus |
cyclin-dependent kinase 5 | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cyclin | - |
Mus musculus |