Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.22 extracted from

  • Bain, J.; McLauchlan, H.; Elliott, M.; Cohen, P.
    The specificities of protein kinase inhibitors: an update (2003), Biochem. J., 371, 199-204.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
cyclin A dependent on Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
alsterpaullone 95% inhibition of CDK2 at 0.01 mM Homo sapiens
indirubin-3'-monoxime 82% inhibition of CDK2 at 0.01 mM Homo sapiens
kenpaullone 78% inhibition of CDK2 at 0.01 mM Homo sapiens
purvalanol 98% inhibition of CDK2 at 0.01 mM Homo sapiens
roscovitine 93% inhibition of CDK2 at 0.01 mM Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
CDK2
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
21
-
assay at room temperature Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens