Literature summary for 2.7.11.21 extracted from

Labella, S.; Woglar, A.; Jantsch, V.; Zetka, M.
Polo kinases establish links between meiotic chromosomes and cytoskeletal forces essential for homolog pairing (2011), Dev. Cell, 21, 948-958.

Search for more literature for 2.7.11.21

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
nuclear envelope	meiotic chromosome pairing centers localize PLK-2 to the nuclear envelope	Caenorhabditis elegans	5635	-

Organism

Organism	UniProt	Comment	Textmining
Caenorhabditis elegans	P34331	-	-
Caenorhabditis elegans	Q9N2L7	-	-

Synonyms

Synonyms	Comment	Organism
PLK-1	-	Caenorhabditis elegans
Plk-2	-	Caenorhabditis elegans

General Information

General Information	Comment	Organism
malfunction	loss of plk-2 inhibits chromosome pairing and licenses synapsis between nonhomologous chromosomes	Caenorhabditis elegans
physiological function	during meiosis the polo kinases PLK-1 is targeted to the pairing center by ZIM/HIM-8-pairing proteins	Caenorhabditis elegans
physiological function	during meiosis the polo kinases PLK-2 is targeted to the pairing center by ZIM/HIM-8-pairing proteins. PLK-2 enzyme is required for pairing center-mediated interhomolog interactions and for meiosis-specific phosphorylation of SUN-1 and establishment of dynamic SUN/KASH (SUN-1/ZYG-12) modules that promote homolog pairing	Caenorhabditis elegans

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Release 2023.1 (January 2023)