Application | Comment | Organism |
---|---|---|
medicine | the skin is an attractive tissue for Plk1 based cancer chemoprevention and chemotherapeutic applications | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
shRNA | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | Homo sapiens | - |
ADP + a phosphoprotein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P53350 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-253 cell | squamous A-253 cell | Homo sapiens | - |
A-431 cell | squamous A-431 cell | Homo sapiens | - |
basal cell carcinoma cell | - |
Homo sapiens | - |
NHEK cell | - |
Homo sapiens | - |
skin | - |
Homo sapiens | - |
squamous cell carcinoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | - |
Homo sapiens | ADP + a phosphoprotein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Plk1 | - |
Homo sapiens |
Polo-like kinase 1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | significantly over-expressed in basal cell carcinoma and squamous cell carcinoma | up |