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Literature summary for 2.7.11.21 extracted from

  • Bachewich, C.; Thomas, D.Y.; Whiteway, M.
    Depletion of a polo-like kinase in Candida albicans activates cyclase-dependent hyphal-like growth (2003), Mol. Biol. Cell, 14, 2163-2180.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information constructed mutant cells deficient in Cdc5p are blocked early in nuclear division with very short spindles and unseparated chromatin, the cell cycle defective mutants show also formation of hyphal-like filaments under yeast growth conditions Candida albicans

Localization

Localization Comment Organism GeneOntology No. Textmining
chromatin unseparated Candida albicans 785
-
nucleus
-
Candida albicans 5634
-
spindle unseparated Candida albicans 5819
-
spindle pole body unseparated Candida albicans 5816
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Candida albicans the polo-loke kinase activates cyclase-dependent hyphal-like growth acting like a switch between yeast and hyphal growth forms, mechanism, overview ?
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?

Organism

Organism UniProt Comment Textmining
Candida albicans
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diverse strains
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the polo-loke kinase activates cyclase-dependent hyphal-like growth acting like a switch between yeast and hyphal growth forms, mechanism, overview Candida albicans ?
-
?

Synonyms

Synonyms Comment Organism
Cdc5p
-
Candida albicans
PLK
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Candida albicans
polo-like kinase
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Candida albicans