Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.18 extracted from

  • Khuon, S.; Liang, L.; Dettman, R.W.; Sporn, P.H.; Wysolmerski, R.B.; Chew, T.L.
    Myosin light chain kinase mediates transcellular intravasation of breast cancer cells through the underlying endothelial cells: a three-dimensional FRET study (2010), J. Cell Sci., 123, 431-440.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.18

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
 Bos taurus
-
pulmonary artery endothelial cell
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + myosin-II regulatory light chain
-
 Bos taurus ADP + myosin-II regulatory light chain phosphate
-
 ?

Synonyms

Synonyms Comment Organism
MLCK
-
 Bos taurus
myosin light chain kinase
-
 Bos taurus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Bos taurus

Expression

Organism Comment Expression
Bos taurus breast cancer cells transiently activate endothelial MLCK at tumor invasion sites up

General Information

General Information Comment Organism
physiological function myosin light chain kinase mediates transcellular intravasation of breast cancer cells through the underlying endothelial cells Bos taurus