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Literature summary for 2.7.11.18 extracted from

  • Suzuki, T.; Nishimukai, M.; Takechi, M.; Taguchi, H.; Hamada, S.; Yokota, A.; Ito, S.; Hara, H.; Matsui, H.
    The nondigestible disaccharide epilactose increases paracellular Ca absorption via Rho-associated kinase- and myosin light chain kinase-dependent mechanisms in rat small intestines (2010), J. Agric. Food Chem., 58, 1927-1932.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
additional information epilactose induces myosin light chain phosphorylation via MLCK Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
ML-7 specific MLCK inhibitor Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
small intestine
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + myosin light chain myosin light chain is phosphorylated at Thr 18 and Ser 19 by myosin light chain kinase Rattus norvegicus ADP + myosin light chain phosphate
-
 ?

Synonyms

Synonyms Comment Organism
MLCK
-
 Rattus norvegicus
myosin light chain kinase
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Rattus norvegicus