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Literature summary for 2.7.11.18 extracted from

  • Zhu, H.Q.; Cheng, X.W.; Xiao, L.L.; Jiang, Z.K.; Zhou, Q.; Gui, S.Y.; Wei, W.; Wang, Y.
    Melatonin prevents oxidized low-density lipoprotein-induced increase of myosin light chain kinase activation and expression in HUVEC through ERK/MAPK signal transduction (2008), J. Pineal Res., 45, 328-334.
    View publication on PubMed
Search for more literature for 2.7.11.18

Activating Compound

Activating Compound Comment Organism Structure
Calmodulin required Homo sapiens
additional information oxidized low density lipoprotein induces the enzyme expression and activation in umbilical vein endothelial cells, which is inhibited by melatonin and PD98059 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required Homo sapiens
Mg2+
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
215000
-
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + myosin light chain Homo sapiens
-
 ADP + myosin light chain phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
umbilical vein endothelial cell i.e. HUVEC Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + myosin light chain
-
 Homo sapiens ADP + myosin light chain phosphate
-
 ?

Synonyms

Synonyms Comment Organism
MLC kinase
-
 Homo sapiens
MLCK
-
 Homo sapiens
myosin light chain kinase
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens