Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.18 extracted from

  • Dudnakova, T.V.; Stepanova, O.V.; Dergilev, K.V.; Chadin, A.V.; Shekhonin, B.V.; Watterson, D.M.; Shirinsky, V.P.
    Myosin light chain kinase colocalizes with nonmuscle myosin IIB in myofibril precursors and sarcomeric Z-lines of cardiomyocytes (2006), Cell Motil. Cytoskeleton, 63, 375-383.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoskeleton
-
Gallus gallus 5856
-
additional information subcellular localization study of MLCK in embryonic cardiomyocytes, overview Gallus gallus
-
-
myofibril
-
Gallus gallus 30016
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + myosin IIB Gallus gallus
-
ADP + phosphorylated myosin IIB
-
?
additional information Gallus gallus the enzyme is a key regulator of various forms of cell motility involving actin and myosin II ?
-
?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cardiomyocyte from embryos, in myofibril precursors and sarcomeric Z-lines, co-localization with myosin IIB Gallus gallus
-
heart left ventricle tissue, MLCK occurs in a cross-striated pattern overlapping with the distribution of alpha-actin Homo sapiens
-
muscle striated, a distinct MLCK isozyme Gallus gallus
-
myocardium adult, MLCK occurs in a cross-striated pattern overlapping with the distribution of alpha-actin Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + myosin IIB
-
Gallus gallus ADP + phosphorylated myosin IIB
-
?
additional information the enzyme is a key regulator of various forms of cell motility involving actin and myosin II Gallus gallus ?
-
?

Synonyms

Synonyms Comment Organism
MLCK
-
Gallus gallus
MLCK
-
Homo sapiens
myosin light chain kinase
-
Gallus gallus
myosin light chain kinase
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Gallus gallus