Literature summary for 2.7.11.18 extracted from

Yanase, M.; Ikeda, H.; Ogata, I.; Matsui, A.; Noiri, E.; Tomiya, T.; Arai, M.; Inoue, Y.; Tejima, K.; Nagashima, K.; Nishikawa, T.; Shibata, M.; Ikebe, M.; Rojkind, M.; Fujiwara, K.
Functional diversity between Rho-kinase- and MLCK-mediated cytoskeletal actions in a myofibroblast-like hepatic stellate cell line (2003), Biochem. Biophys. Res. Commun., 305, 223-228.

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Inhibitors

Inhibitors	Comment	Organism	Structure
ML-7	calmodulin/enzyme-specific inhibitor, inhibits cell attachment to extracellular substrate in vivo, attenuates the activation of GTP-binding protein Rac and cell migration	Rattus norvegicus
W-7	calmodulin/enzyme-specific inhibitor, attenuates cell migration in vivo	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Kupffer cell	myofibroblast-like stellate cell line, previously called Ito cells, lipocytes, or fat-storing cells	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
MLCK	-	Rattus norvegicus

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Rattus norvegicus
Calmodulin	-	Rattus norvegicus

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Release 2023.1 (January 2023)