Literature summary for 2.7.11.15 extracted from

Inagaki, S.; Ghirlando, R.; Vishnivetskiy, S.A.; Homan, K.T.; White, J.F.; Tesmer, J.J.; Gurevich, V.V.; Grisshammer, R.
G protein-coupled receptor kinase 2 (GRK2) and 5 (GRK5) exhibit selective phosphorylation of the neurotensin receptor in vitro (2015), Biochemistry, 54, 4320-4329.

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Protein Variants

Protein Variants	Comment	Organism
S670A	inactive	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + [neurotensin receptor]	Homo sapiens	the enzyme phosphorylates only the C-terminal serine residues	ADP + phospho-[neurotensin receptor]	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + [neurotensin receptor]	the enzyme phosphorylates only the C-terminal serine residues	Homo sapiens	ADP + phospho-[neurotensin receptor]	-	?

Synonyms

Synonyms	Comment	Organism
G protein-coupled receptor kinase 2	-	Homo sapiens
GRK2	-	Homo sapiens

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Release 2023.1 (January 2023)