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Literature summary for 2.7.11.15 extracted from

  • Le Sommer, C.; Barrows, N.; Bradrick, S.; Pearson, J.; Garcia-Blanco, M.
    G Protein-coupled receptor kinase 2 promotes flaviviridae entry and replication (2012), PLoS Negl. Trop. Dis., 6, e1820.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
embryonic fibroblast cell line
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Mus musculus
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Synonyms

Synonyms Comment Organism
GRK2
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Mus musculus

General Information

General Information Comment Organism
malfunction using siRNA-mediated knockdown of GRK2 in mouse embryonic fibroblasts it is shown that GRK2 is required for efficient propagation of viruses from the Flaviviridae family and that a decrease in GRK2 level alters both virus entry and RNA genome amplification Mus musculus