Activating Compound | Comment | Organism | Structure |
---|---|---|---|
phorbol 12-myristate 13-acetate | - |
Mus musculus |
Cloned (Comment) | Organism |
---|---|
overexpression PKCdelta in NMuMG cells, a normal immortalized mammary cell line derived from NAMRU mice | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | depletion of PKCdelta using RNAi leads to a marked increase in both urokinase-type plasminogen activator and matrix metalloproteinase-9 secretion, while PKCdelta overexpression significantly decreases urokinase-type plasminogen activator and matrix metalloproteinase-9 production, two proteases associated with migratory and invasive capacities | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
78000 | - |
x * 78000, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | isozyme PKCdelta inhibits the production of proteolytic enzymes in murine mammary cells, the PKCdelta effect is mediated by the MEK/ERK pathway, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
isozyme PKCdelta | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mammary gland | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | isozyme PKCdelta inhibits the production of proteolytic enzymes in murine mammary cells, the PKCdelta effect is mediated by the MEK/ERK pathway, overview | Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 78000, SDS-PAGE | Mus musculus |