Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.12 extracted from

  • Kawasaki, Y.; Kugimiya, F.; Chikuda, H.; Kamekura, S.; Ikeda, T.; Kawamura, N.; Saito, T.; Shinoda, Y.; Higashikawa, A.; Yano, F.; Ogasawara, T.; Ogata, N.; Hoshi, K.; Hofmann, F.; Woodgett, J.R.; Nakamura, K.; Chung, U.I.; Kawaguchi, H.
    Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes (2008), J. Clin. Invest., 118, 2506-2515.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.12

Application

Application Comment Organism
medicine cGKII deficiency leads to dwarfism in mice as consequence of an elongated growth plate and impaired chondrocyte hypertrophy Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus Q61410
-
-

Source Tissue

Source Tissue Comment Organism Textmining
chondrocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + glycogen synthase kinase-3beta
-
 Mus musculus ADP + phosphorylated glycogen synthase kinase-3beta
-
 ?

Synonyms

Synonyms Comment Organism
cGK-II
-
 Mus musculus
cGMP-dependent protein kinase II
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus
cGMP dependent Mus musculus