Literature summary for 2.7.11.12 extracted from

Sharma, A.K.; Zhou, G.P.; Kupferman, J.; Surks, H.K.; Christensen, E.N.; Chou, J.J.; Mendelsohn, M.E.; Rigby, A.C.
Probing the interaction between the coiled-coil leucine zipper of cGMP-dependent protein kinase Ialpha and the C-terminus of the myosin binding subunit of the myosin light chain phosphatase (2008), J. Biol. Chem., 283, 32860-32869.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli, with glutathione-S-transferase-fusion tag	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni2+-NTA agarose column chromatography and Superdex 75 gel filtration	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + myosin phosphatase	-	Homo sapiens	ADP + phosphorylated RhoA	-	?

Synonyms

Synonyms	Comment	Organism
cGMP-dependent protein kinase Ialpha	-	Homo sapiens
PKG-Ialpha	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Homo sapiens
cGMP	dependent	Homo sapiens

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Release 2023.1 (January 2023)