Cloned (Comment) | Organism |
---|---|
adenoviral transfection of rat adult cardiomyocytes with the human isozyme PKGIalpha and its catalytically inactive mutant PKGIalphaK390A | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | overexpression of active PKGIalpha, but not of the inactive mutant K390A, increases of Akt and inhibits necrosis and apoptosis in cardiomyocytes, overview | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + Akt | Homo sapiens | - |
ADP + phosphorylated Akt | - |
? | |
additional information | Homo sapiens | PKG Ialpha attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isozymes PKGIalpha and PKGIbeta | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cardiomyocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + Akt | - |
Homo sapiens | ADP + phosphorylated Akt | - |
? | |
ATP + Akt | phosphorylation at Ser473 | Homo sapiens | ADP + phosphorylated Akt | - |
? | |
additional information | PKG Ialpha attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKGIalpha | - |
Homo sapiens |
PKGIbeta | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |