Protein Variants | Comment | Organism |
---|---|---|
additional information | PKGII-deficient mice are defective in renal functiona regulation, and in resetting the circadian clock because light induction of mPer2 gene in the hypothalamus is strongly reduced in the early peroid of the night, whereas mPer1 gene induction is elevated | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | PKGII modulates mPer1 and mPer2 gene induction, not by phosphorylation of CREB at Ser133, and influences phase shifts of the circadian clock, regulation model, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hypothalamus | - |
Mus musculus | - |
suprachiasmatic nucleus | of the hypothalamus | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | PKGII modulates mPer1 and mPer2 gene induction, not by phosphorylation of CREB at Ser133, and influences phase shifts of the circadian clock, regulation model, overview | Mus musculus | ? | - |
? | |
additional information | no activity with the cAMP-responsive element binding protein, i.e. CREB | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cGKII | - |
Mus musculus |
cGMP-dependent protein kinase II | - |
Mus musculus |
PKGII | - |
Mus musculus |