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Literature summary for 2.7.11.11 extracted from
- cAMP-dependent protein kinase (PKA) signaling is impaired in the diabetic heart (2015), J. Biol. Chem., 290, 29250-29258.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| 8-bromo-cAMP | - |
Mus musculus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Mus musculus | 5737 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + phosphofructokinase 2 | Mus musculus | - |
ADP + phosphorylated phosphofructokinase 2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cardiomyocyte | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + phosphofructokinase 2 | - |
Mus musculus | ADP + phosphorylated phosphofructokinase 2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PKA | - |
Mus musculus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Mus musculus | enzyme activity is impaired in diabetes | down |
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Release 2023.1 (January 2023)
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