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Literature summary for 2.7.11.11 extracted from

  • Bond, S.; Forgac, M.
    The Ras/cAMP/protein kinase A pathway regulates glucose-dependent assembly of the V-ATPase in yeast (2008), J. Biol. Chem., 283, 36513-36521.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information Ras stimulates adenylate cyclase leading to increasing cAMP levels and in turn increased activity of protein kinase A Saccharomyces cerevisiae

Inhibitors

Inhibitors Comment Organism Structure
additional information GTPase activating proteins negatively regulate Ras in nutrient-poor conditions, downregulation of Ras lowers cAMP levels leading to reduced activity of protein kinase A Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Synonyms

Synonyms Comment Organism
PKA
-
Saccharomyces cerevisiae
protein kinase A
-
Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
ATP
-
Saccharomyces cerevisiae
cAMP dependent Saccharomyces cerevisiae