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Literature summary for 2.7.11.11 extracted from

  • Crawford, A.T.; Desai, D.; Gokina, P.; Basak, S.; Kim, H.A.
    E-cadherin expression in postnatal Schwann cells is regulated by the cAMP-dependent protein kinase A pathway (2008), Glia, 56, 1637-1647.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.11

Activating Compound

Activating Compound Comment Organism Structure
dibutyryl-cAMP
-
 Rattus norvegicus
forskolin 0.005 mM for 48 h Rattus norvegicus
additional information not stimulated by glial growth factor, sensory and motor neuron derived factor, or platelet-derived growth factor Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
H-89
-
 Rattus norvegicus
myristoylated-PKI cAMP-PKA-specific inhibitory peptide PKI Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus cAMP elevation in the Schwann cell is sufficient to induce E-cadherin expression accompanied by suppression of N-cadherin expression ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
ganglion dorsal root ganglion Rattus norvegicus
-
Schwann cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Kemptide
-
 Rattus norvegicus ADP + Kemptide phosphate
-
 ?
additional information cAMP elevation in the Schwann cell is sufficient to induce E-cadherin expression accompanied by suppression of N-cadherin expression Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
cAMP-PKA
-
 Rattus norvegicus
protein kinase A
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Rattus norvegicus
cAMP dependent Rattus norvegicus