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Literature summary for 2.7.11.11 extracted from

  • Lecureuil, C.; Tesseraud, S.; Kara, E.; Martinat, N.; Sow, A.; Fontaine, I.; Gauthier, C.; Reiter, E.; Guillou, F.; Crepieux, P.
    Follicle-stimulating hormone activates p70 ribosomal protein S6 kinase by protein kinase A-mediated dephosphorylation of Thr 421/Ser 424 in primary Sertoli cells (2005), Mol. Endocrinol., 19, 1812-1820.
    View publication on PubMed
Search for more literature for 2.7.11.11

Activating Compound

Activating Compound Comment Organism Structure
cAMP
-
 Rattus norvegicus
forskolin
-
 Rattus norvegicus
additional information dephosphorylation activity induced by the pituitary follicle-stimulating hormone FSH Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + ribosomal S6 protein Rattus norvegicus
-
 ADP + phosphorylated ribosomal S6 protein
-
 ?
additional information Rattus norvegicus induced by the pituitary follicle-stimulating hormone FSH PKA also catalyzes the dephosphorylation of residues T421 and S424 of the autoinhibitory domain of p70S6K, resulting in activation of p70S6K important for differentiation of Sertoli cells in male reproduction, regulation overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Sertoli cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + ribosomal S6 protein
-
 Rattus norvegicus ADP + phosphorylated ribosomal S6 protein
-
 ?
additional information induced by the pituitary follicle-stimulating hormone FSH PKA also catalyzes the dephosphorylation of residues T421 and S424 of the autoinhibitory domain of p70S6K, resulting in activation of p70S6K important for differentiation of Sertoli cells in male reproduction, regulation overview Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
PKA
-
 Rattus norvegicus
protein kinase A
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Rattus norvegicus