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Literature summary for 2.7.11.11 extracted from

  • West, G.A.; Meno, J.R.; Nguyen, T.S.; Ngai, A.C.; Simard, J.M.; Winn, H.R.
    cGMP-dependent and not cAMP-dependent kinase is required for adenosine-induced dilation of intracerebral arterioles (2003), J. Cardiovasc. Pharmacol., 41, 444-451.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
8-bromo-cAMP
-
 Rattus norvegicus
cAMP
-
 Rattus norvegicus
forskolin
-
 Rattus norvegicus
additional information no enzyme activation or induction by adenosine Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
Rp-8-CPT-cAMPS
-
 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus the enzyme is not required for adenosine-induced dilation of intracerebral arterioles and regulation of cerebral blood flow ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male sprague-dawley rats
-

Source Tissue

Source Tissue Comment Organism Textmining
arteriole cerebral, microvascular, isolated from cortical vessels Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is not required for adenosine-induced dilation of intracerebral arterioles and regulation of cerebral blood flow Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
PKA
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Rattus norvegicus