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Literature summary for 2.7.11.11 extracted from

  • Barman, S.A.; Zhu, S.; Han, G.; White, R.E.
    cAMP activates BKCa channels in pulmonary arterial smooth muscle via cGMP-dependent protein kinase (2003), Am. J. Physiol., 284, L1004-1011.
    View publication on PubMed
Search for more literature for 2.7.11.11

Activating Compound

Activating Compound Comment Organism Structure
cAMP dependent on Rattus norvegicus
additional information forskolin activates via stimulation of cAMP production Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
KT5720 PKA inhibitor Rattus norvegicus
additional information no inhibition by KT5823 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus cAMP-dependent activation of BKCa channels in pulmonary arterial smooth muscle is not catalyzed by PKA but by cGMP-dependent protein kinase PKG, thus PKA is not involved in cAMP-induced signaling in pulmonary vasodilation ?
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
 Rattus norvegicus
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smooth muscle pulmonary arterial Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cAMP-dependent activation of BKCa channels in pulmonary arterial smooth muscle is not catalyzed by PKA but by cGMP-dependent protein kinase PKG, thus PKA is not involved in cAMP-induced signaling in pulmonary vasodilation Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
PKA
-
 Rattus norvegicus