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Literature summary for 2.7.11.10 extracted from

  • Caposio, P.; Dreano, M.; Garotta, G.; Gribaudo, G.; Landolfo, S.
    Human cytomegalovirus stimulates cellular IKK2 activity and requires the enzyme for productive replication (2004), J. Virol., 78, 3190-3195.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.10

Activating Compound

Activating Compound Comment Organism Structure
additional information infection and genome insertion of human cytomegalovirus induces expression of the catalytic subunit IKK2 in the host cell which is required for viral induction of NF-kappaB activation and involved in viral replication and lytic cycle Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
transient expression of wild-type and mutant FLAG-tagged IKK2 in HELF cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
K44A site-directed mutagenesis of subunit IKK2, catalytically inactive mutant and no NF-kappaB stimulation in infected cells in vivo Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
AS602868
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens infection and genome insertion of human cytomegalovirus induces expression of the catalytic subunit IKK2 in the host cell which is required for viral induction of NF-kappaB activation and involved in viral replication and lytic cycle ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information infection and genome insertion of human cytomegalovirus induces expression of the catalytic subunit IKK2 in the host cell which is required for viral induction of NF-kappaB activation and involved in viral replication and lytic cycle Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
More subunits IKK1 and IKK2 Homo sapiens

Synonyms

Synonyms Comment Organism
IKK
-
 Homo sapiens