Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Mycobacterium tuberculosis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
staurosporine | inhibits phosphorylation of myelin basic proteins | Mycobacterium tuberculosis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | deduced amino acid sequence contains two transmembrane segments, which flank a highly repetitive region, suggesting a receptor-like anchoring | Mycobacterium tuberculosis | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | required | Mycobacterium tuberculosis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
70000 | - |
x * 70000 | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | P9WI79 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | autophosphorylation on Thr | Mycobacterium tuberculosis |
Purification (Comment) | Organism |
---|---|
recombinant enzyme is purified as a fusion protein with gluthatione S-transferase | Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | autophosphorylation on Thr | Mycobacterium tuberculosis | ADP + a phosphoprotein | - |
? | |
ATP + histone | histones from calf thymus, phosphorylation on Ser | Mycobacterium tuberculosis | ADP + phosphorylated histone | - |
? | |
ATP + myelin basic protein | myelin basic proteins from bovine brain, phosphorylation on Ser | Mycobacterium tuberculosis | ADP + phosphorylated myelin basic protein | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 70000 | Mycobacterium tuberculosis |
Synonyms | Comment | Organism |
---|---|---|
serine/threonine-protein kinase pknD | - |
Mycobacterium tuberculosis |