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Literature summary for 2.7.11.1 extracted from

  • Brown, J.L.; Stowers, L.; Baer, M.; Trejo, J.; Coughlin, S.; Chant, J.
    Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway (1996), Curr. Biol., 6, 598-605.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + protein Homo sapiens hPAK1 is a GTPase effector controlling a downstream MAP kinase pathway. PAK kinase plays a key part in linking extracellular signals from membrane components, such as receptor-associated G proteins and Rho-related GTPases, to nuclear responses, such as transcriptional activation ADP + phosphoprotein
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Organism

Organism UniProt Comment Textmining
Homo sapiens Q13153
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + protein hPAK1 is a GTPase effector controlling a downstream MAP kinase pathway. PAK kinase plays a key part in linking extracellular signals from membrane components, such as receptor-associated G proteins and Rho-related GTPases, to nuclear responses, such as transcriptional activation Homo sapiens ADP + phosphoprotein
-
?

Synonyms

Synonyms Comment Organism
hPAK1
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Homo sapiens
serine/threonine-protein kinase PAK 1
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Homo sapiens