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Literature summary for 2.7.10.2 extracted from

  • Montresor, A.; Bolomini-Vittori, M.; Toffali, L.; Rossi, B.; Constantin, G.; Laudanna, C.
    JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation (2013), J. Cell Biol., 203, 1003-1019.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.10.2

Activating Compound

Activating Compound Comment Organism Structure
CXCL12
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
120000
-
 x * 120000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a [protein]-L-tyrosine Homo sapiens
-
 ADP + a [protein]-L-tyrosine phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a [protein]-L-tyrosine
-
 Homo sapiens ADP + a [protein]-L-tyrosine phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 120000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
JAK2
-
 Homo sapiens
Jak3
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function JAK tyrosine kinases control integrin activation and dependent lymphocyte trafficking by bridging chemokine receptors to the concurrent and hierarchical activation of the Rho and Rap modules of integrin activation Homo sapiens