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Literature summary for 2.7.10.2 extracted from
- ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells (2008), J. Biol. Chem., 283, 27230-27238.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | Abl1 and Abl2 have a role in axonogenesis and cancer | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| into the pcDNA3.1 TOPO vector | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| siRNA | - |
Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Homo sapiens | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + [protein]-L-tyrosine | Homo sapiens | - |
ADP + [protein]-L-tyrosine phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| endothelial cell | - |
Homo sapiens | - |
| U-87MG cell | - |
Homo sapiens | - |
| umbilical vein endothelial cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + [protein]-L-tyrosine | - |
Homo sapiens | ADP + [protein]-L-tyrosine phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Abelson tyrosine kinase | - |
Homo sapiens |
| ABL2 | - |
Homo sapiens |
| ABL2/ARG tyrosine kinase | - |
Homo sapiens |
| ARG | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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