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Literature summary for 2.7.10.2 extracted from

  • Aubele, M.; Walch, A.K.; Ludyga, N.; Braselmann, H.; Atkinson, M.J.; Luber, B.; Auer, G.; Tapio, S.; Cooke, T.; Bartlett, J.M.
    Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients (2008), Br. J. Cancer, 99, 1089-1095.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.10.2

Application

Application Comment Organism
medicine PTK6 may serve as a future target for the development of novel treatments in breast cancer Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [protein]-L-tyrosine Homo sapiens
-
 ADP + [protein]-L-tyrosine phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q13882
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell
-
 Homo sapiens
-
T-47D cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [protein]-L-tyrosine
-
 Homo sapiens ADP + [protein]-L-tyrosine phosphate
-
 ?
ATP + [Sam68]-L-tyrosine
-
 Homo sapiens ADP + [Sam68]-L-tyrosine phosphate
-
 ?

Synonyms

Synonyms Comment Organism
breast tumour kinase
-
 Homo sapiens
Brk
-
 Homo sapiens
protein tyrosine kinase 6
-
 Homo sapiens
PTK6
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens