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Literature summary for 2.7.10.2 extracted from
- The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP (1993), Proc. Natl. Acad. Sci. USA, 90, 442-446.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| K273R | mutant protein is unable to transfer the gamma-phosphate of ATP but able to bind 8-azido-ATP with an efficiency similar to that of wild-type pp56lck | Mus musculus |
| additional information | generation of mutants of the protein-tyrosine kinase pp56lck that have single amino acid substitutions within the area surrounding the conserved residue Lys-273 in subdomain II. When compared with wild-type pp56lck, these mutants display profound reductions in their phosphotransfer efficiencies and small differences in their affinities for ATP | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P06240 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| pp56lck | - |
Mus musculus |
| proto-oncogene tyrosine-protein kinase LCK | - |
Mus musculus |
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Release 2023.1 (January 2023)
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