Literature summary for 2.7.10.1 extracted from

Zeren, T.; Inan, S.; Seda Vatansever, H.; Ekerbicer, N.; Sayhan, S.
Significance of tyrosine kinase activity on malign transformation of ovarian tumors: a comparison between EGF-R and TGF-alpha (2008), Acta Histochem., 110, 256-263.

Search for more literature for 2.7.10.1

Application

Application	Comment	Organism
medicine	EGF-R may be a more useful marker than TGF-alpha in epithelial ovarian tumors. Increased EGF-R immunoreactivtiy in tumors with greater malignant potential, indicating that EGF-R may be a suitable target for more effective therapeutic approaches to ovarian carcinoma	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	invasive cancers	Homo sapiens	5737	-
membrane	borderline tumors and invasive cancers	Homo sapiens	16020	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
epithelium	-	Homo sapiens	-
ovary cancer cell	EGF-R is moderately present in serous and mucinous borderline tumors and increases in adenocarcinomas, whereas TGF-alpha is moderately present	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
EGF-R	-	Homo sapiens
epidermal growth factor-receptor	-	Homo sapiens
receptor tyrosine kinase	-	Homo sapiens

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Release 2023.1 (January 2023)