Literature summary for 2.7.10.1 extracted from

Vincent, C.; Doublet, P.; Grangeasse, C.; Vaganay, E.; Cozzone, A.J.; Duclos, B.
Cells of Escherichia coli contain a protein-tyrosine kinase, Wzc, and a phosphotyrosine-protein phosphatase, Wzb (1999), J. Bacteriol., 181, 3472-3477.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Escherichia coli	phosphotyrosine-protein phosphatase Wzb is able to dephosphorylate previously autophosphorylated Wzc. Reversible protein phosphorylation on tyrosine may be part of the cascade of reactions that determine the pathogenicity of bacteria	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P76387	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + tyrosine-protein kinase Wcz	efficient autophosphorylation in presence of ATP	Escherichia coli	ADP + phosphotyrosine-protein kinase Wcz	-	?
additional information	phosphotyrosine-protein phosphatase Wzb is able to dephosphorylate previously autophosphorylated Wzc. Reversible protein phosphorylation on tyrosine may be part of the cascade of reactions that determine the pathogenicity of bacteria	Escherichia coli	?	-	?

Synonyms

Synonyms	Comment	Organism
tyrosine-protein kinase Wzc	-	Escherichia coli

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Release 2023.1 (January 2023)