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Literature summary for 2.7.1.95 extracted from

  • Heng, B.C.; Cao, T.
    Immunoliposome-mediated delivery of neomycin phosphotransferase for the lineage-specific selection of differentiated/committed stem cell progenies: potential advantages over transfection with marker genes, fluorescence-activated and magnetic affinity cell-sorting (2005), Med. Hypotheses, 65, 334-336.
    View publication on PubMed

Application

Application Comment Organism
medicine the enzyme can be used in immunoliposome-mediated delivery for the lineage-specific selection of differentiated/committed stem cell progenies for transplantation, method development and evaluation, potential advantages over transfection with marker genes, fluorescence-activated and magnetic affinity cell-sorting, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + neomycin Homo sapiens
-
ADP + neomycin 3'-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + neomycin
-
Homo sapiens ADP + neomycin 3'-phosphate
-
?
ATP + neomycin i.e. G418, specific inactivation of the antibiotic Homo sapiens ADP + neomycin 3'-phosphate
-
?

Synonyms

Synonyms Comment Organism
neomycin phosphotransferase
-
Homo sapiens
NPT
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens