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Literature summary for 2.7.1.94 extracted from
- The biosynthesis of phosphatidic acid and lysophosphatidic acid by glyceride phosphokinase pathways in escherichia coli (1965), J. Biol. Chem., 240, 2833-2838.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Cutsum | no absolute requirement, optimal concentration: 0.1% | Escherichia coli |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| particle-bound | - |
Escherichia coli | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | requirement for divalent cation is best fulfilled by Mg2+. Mn2+, Zn2+ and Ca2+, in that order are fair to poor substitutes for Mg2+ | Escherichia coli |  |
| Mg2+ | required | Escherichia coli | |
| Mg2+ | requirement for divalent cation is best fulfilled by Mg2+. Mn2+, Zn2+ and Ca2+, in that order are fair to poor substitutes for Mg2+, optimal concentration of Mg2+ is 0.03 M | Escherichia coli | |
| Mn2+ | requirement for divalent cation is best fulfilled by Mg2+. Mn2+, Zn2+ and Ca2+, in that order are fair to poor substitutes for Mg2+ | Escherichia coli | |
| Zn2+ | requirement for divalent cation is best fulfilled by Mg2+. Mn2+, Zn2+ and Ca2+, in that order are fair to poor substitutes for Mg2+ | Escherichia coli | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
| Escherichia coli B / ATCC 11303 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1,2-dipalmitoylglycerol | - |
Escherichia coli | ADP + 1,2-dipalmitoylglycerol 3-phosphate | product identified as alpha-phosphatidic acid | ? | |
| ATP + 1,2-dipalmitoylglycerol | - |
Escherichia coli B / ATCC 11303 | ADP + 1,2-dipalmitoylglycerol 3-phosphate | product identified as alpha-phosphatidic acid | ? | |
| ATP + 1-palmitoylglycerol | - |
Escherichia coli | ADP + 1-palmitoylglycerol 3-phosphate | - |
? | |
| ATP + 1-palmitoylglycerol | - |
Escherichia coli B / ATCC 11303 | ADP + 1-palmitoylglycerol 3-phosphate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Escherichia coli |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | 7.5 | about 35% of maximal activity at pH 6.5 and pH 7.5 | Escherichia coli |
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Release 2023.1 (January 2023)
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