Cloned (Comment) | Organism |
---|---|
expressed in HEK -293T cells and embryonal carcinoma cells | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | site-directed mutagenesis at Cys-4 and Cys-5 residues results in increased sphingosine kinase activity | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mus musculus | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
34000 | - |
SDS-PAGE | Mus musculus |
43000 | - |
SDS-PAGE | Mus musculus |
43300 | - |
calculated from sequence of cDNA | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Mus musculus | Q8CI15 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
heart | - |
Mus musculus | - |
kidney | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
skeletal muscle | - |
Mus musculus | - |
spleen | - |
Mus musculus | - |
testis | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + sphingosine | - |
Mus musculus | ADP + sphingosine 1-phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 43000, SDS-PAGE | Mus musculus |
oligomer | - |
Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
sphingosine kinase type 1 | - |
Mus musculus |
SPHK1a | stable enzyme form | Mus musculus |
SPHK1b | unstable enzyme form | Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |