Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | SPHK2 is not activated by transforming growth factor beta1 | Homo sapiens | |
transforming growth factor beta1 | 5ng/ml | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(p-hydroxyanilino)-4-(p-chlorophenyl) thiazole | 0.005 mM | Homo sapiens | |
N,N-dimethylsphingosine | 0.005 mM | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9NRA0 | - |
- |
Homo sapiens | Q9NYA1 | - |
- |
Mus musculus | Q8CI15 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bronchial epithelial cell | - |
Mus musculus | - |
lung fibroblast | - |
Homo sapiens | - |
lung fibroblast | - |
Mus musculus | - |
smooth muscle cell | - |
Mus musculus | - |
vascular endothelial cell | - |
Mus musculus | - |
WI-38 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + sphingosine | - |
Homo sapiens | ADP + sphingosine 1-phosphate | - |
? | |
ATP + sphingosine | - |
Mus musculus | ADP + sphingosine 1-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
sphingosine kinase 1 | - |
Homo sapiens |
sphingosine kinase 1 | - |
Mus musculus |
sphingosine kinase 2 | - |
Homo sapiens |
SPHK1 | - |
Homo sapiens |
SPHK1 | - |
Mus musculus |
SPHK2 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens | |
ATP | - |
Mus musculus |