Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D,L-threo-dihydrosphingosine | - |
Rattus norvegicus | |
N,N-dimethylsphingosine | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
D-(+)-erythro-sphinganine | - |
Rattus norvegicus | |
0.093 | - |
ATP | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | maximal activity at 5-10 mM | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
49000 | - |
gel filtration | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-(+)-erythro-sphinganine | - |
Rattus norvegicus | ADP + D-(+)-erythro-sphinganine 1-phosphate | - |
? | |
ATP + sphinganine | - |
Rattus norvegicus | ADP + sphinganine 1-phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 49000, SDS-PAGE | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.6 | 7.5 | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
D,L-threo-dihydrosphingosine | - |
Rattus norvegicus | |
0.01 | - |
N,N-dimethylsphingosine | - |
Rattus norvegicus |