Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.76 extracted from

  • Sandrini, M.P.; Shannon, O.; Clausen, A.R.; Bjoerck, L.; Piskur, J.
    Deoxyribonucleoside kinases activate nucleoside antibiotics in severely pathogenic bacteria (2007), Antimicrob. Agents Chemother., 51, 2726-2732.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.76

Cloned(Commentary)

Cloned (Comment) Organism
-
 Staphylococcus aureus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0292
-
 2'-deoxyadenosine pH 8.0 Staphylococcus aureus
0.0344
-
 2'-deoxycytidine pH 8.0 Staphylococcus aureus
0.192
-
 2',2'-difluorodesoxycytidine pH 8.0 Staphylococcus aureus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
26400
-
 x * 26400, calculated Staphylococcus aureus

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus Q0H0H0
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 2',2'-difluorodeoxycytidine
-
 Staphylococcus aureus ADP + 2',2'-difluorodeoxycytidine 5'-phosphate
-
 ?
ATP + 2'-deoxyadenosine
-
 Staphylococcus aureus ADP + 2'-deoxyadenosine 5'-phosphate
-
 ?
ATP + 2'-deoxycytidine
-
 Staphylococcus aureus ADP + 2'-deoxycytidine 5'-phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 26400, calculated Staphylococcus aureus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.19
-
 2',2'-difluorodeoxycytidine pH 8.0 Staphylococcus aureus
0.56
-
 2'-deoxycytidine pH 8.0 Staphylococcus aureus
1.82
-
 2'-deoxyadenosine pH 8.0 Staphylococcus aureus