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Literature summary for 2.7.1.68 extracted from

  • Kisseleva, M.; Feng, Y.; Ward, M.; Song, C.; Anderson, R.A.; Longmore, G.D.
    The LIM protein Ajuba regulates phosphatidylinositol 4,5-bisphosphate levels in migrating cells through an interaction with and activation of PIPKI alpha (2005), Mol. Cell. Biol., 25, 3956-3966.
    View publication on PubMedView publication on EuropePMC
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Activating Compound

Activating Compound Comment Organism Structure
Ajuba dramatic activation of enzymatic activity Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Sf9 cells and MEF cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Talon metal affinity column chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
keratinocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 Homo sapiens ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?

Synonyms

Synonyms Comment Organism
PI(4)P 5-kinase
-
 Homo sapiens
PIPKIalpha
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens