Literature summary for 2.7.1.68 extracted from

Oude Weernink, P.A.; Schulte, P.; Guo, Y.; Wetzel, J.; Amano, M.; Kaibuchi, K.; Haverland, S.; Voss, M.; Schmidt, M.; Mayr, G.W.; Jakobs, K.H.
Stimulation of phosphatidylinositol-4-phosphate 5-kinase by Rho-kinase (2000), J. Biol. Chem., 275, 10168-10174.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate	Homo sapiens	Rho-kinase is involved in the Rho-controlled synthesis of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate by phosphatidylinositol-4-phosphate 5-kinase	ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HEK-293 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate	Rho-kinase is involved in the Rho-controlled synthesis of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate by phosphatidylinositol-4-phosphate 5-kinase	Homo sapiens	ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate	-	?

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Release 2023.1 (January 2023)